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Symptoms include bluish skin, dilated pupils, slowed pulse and breathing, low blood pressure and loss of consciousness. In severe cases, a person’s heart can stop beating, and they may require CPR.
Hypothermia should be treated first, if present, by bringing core body temperature above 35 degrees Celsius. [ 6 ] [ 10 ] Raynaud's phenomenon: An abnormal spasming of blood vessels often in the tips of fingers and toes - usually in response to strong emotions or cold exposure. [ 8 ]
Symptoms depend on the temperature. In mild hypothermia, there is shivering and mental confusion. In moderate hypothermia, shivering stops and confusion increases. [3] In severe hypothermia, there may be hallucinations and paradoxical undressing, in which a person removes their clothing, as well as an increased risk of the heart stopping. [2]
Frostbite is a skin injury that occurs when someone is exposed to extremely low temperatures, causing the freezing of the skin or other tissues, [1] commonly affecting the fingers, toes, nose, ears, cheeks and chin areas. [6]
Wythenshawe Hospital was a founding member of the Manchester Academic Health Science Centre [10] and a teaching hospital of Manchester Medical School. [11] [12] [13] [14]It is still a centre of expertise in respiratory disease and the North West Lung Centre houses the Adult Cystic Fibrosis Centre and the UK National Aspergillosis Centre.
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One of the major symptoms of Shapiro syndrome is the hypothermia. Clonidine , an alpha 2-adrenoreceptor agonist, is a medication commonly used for hypertension. However, clonidine has been found to aid in hypothalamic regulation and is the most effective medication for symptom management in Shapiro syndrome . [ 5 ]
Oxford Road, Manchester, Greater Manchester, England Coordinates 53°27′36″N 2°13′38″W / 53.4599645°N 2.2271186°W / 53.4599645; -2.2271186