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I-44 follows the general route of, and completely replaced, historic US 66 from Halltown (exit 58, the junction with a cutoff section of US 66 since renumbered as Route 96) to downtown St. Louis. From rural Joplin at exit 15 to Mount Vernon at exit 49, it largely follows a decommissioned section of US 166 .
U.S. Route 150 (US 150) in Kentucky is a 121.097-mile-long (194.887 km) east–west highway that runs from the Indiana state line above the Ohio River to US 25/KY 1249 at Mount Vernon. Route description
The St. Louis region’s port system is the second-largest inland port system in the United States, and was ranked the most efficient port system by the U.S. Army Corps of Engineers. The St. Louis regional port system is responsible for 8% of the 855 miles of the Mississippi River, but carries one-third of the river’s total freight. [42]
MetroBus is a public bus service operated by Metro Transit that serves the Greater St. Louis area. In 2023, the service had an annual ridership of 12,531,400, or about 41,400 per weekday as of the third quarter of 2024.
I-55/I-64/US 40 in East St. Louis: I-70/US 40 near Marshall ... Served East St. Louis: US 66 Bus. ... Served Mount Vernon
Moving Transit Forward also identified five potential bus rapid transit lines. Four would have run along highways that connect downtown St. Louis to its suburbs: I-44 to Eureka, I-64 to Chesterfield, I-55 to South County, and I-70 to St. Charles County. A fifth line would have run along Grand Boulevard in St. Louis. [134]
I-44 / I-55 in St. Louis. I-55/I-64 travels concurrently to East, St. Louis, Illinois. Illinois I-55 / I-70 / US 40 in East St. Louis I-255 / US 50 in Caseyville. I-64/US 50 travels concurrently to O'Fallon. US 51 in Richview I-57 in Mount Vernon. The highways travel concurrently to south-southwest of Mount Vernon. US 45 north of Mill Shoals ...
Mount Vernon is the only major city and intersection served by I-64 in Illinois outside of the St. Louis metropolitan area. [3] [1] Past Mount Vernon, the Interstate enters another rural stretch through parts of Jefferson, Wayne, and White counties before crossing the Wabash River into Indiana. [3]