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Minoxidil, applied topically, is widely used for the treatment of hair loss. It may be effective in helping promote hair growth in both men and women with androgenic alopecia. [20] [21] About 40% of men experience hair regrowth after 3–6 months. [22] It is the only topical product that is FDA approved in America for androgenic hair loss. [20]
Because of its long elimination half-life, dutasteride requires 5 to 6 months to reach steady-state concentrations. [59] It also remains in the body for a long time after discontinuation and can be detected up to 4 to 6 months. [1] [2] In contrast to dutasteride, finasteride has a short terminal half-life of only 5 to 8 hours.
Finasteride Blocks DHT to Stop Hair Loss. Finasteride is one of two 5-alpha reductase inhibitors, along with dutasteride. 5-alpha reductase is an enzyme that your body eventually converts into a ...
Finasteride and dutasteride are both 5-alpha reductase inhibitor medications that stop your body from converting testosterone into DHT, a hormone that causes male pattern hair loss.
Dutasteride was approved for the treatment of BPH in 2001 and was subsequently approved for pattern hair loss in South Korea in 2009 and in Japan in 2015. [ 44 ] [ 45 ] The patent protection on finasteride and dutasteride has expired and both drugs are available as generic medications .
3. Medications. Some medications have been associated with temporary hair loss. Most of the time hair loss related to medication is due to the drug disrupting the hair growth cycle leading to a ...