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Different classes of hallucinogens have different pharmacological mechanisms of action. [2] [69] Psychedelics are 5-HT 2A receptor agonists (serotonin 2A receptor agonists). [70] [69] LSD, mescaline, psilocybin, and PCP are drugs that cause hallucinations, which can alter a person's perception of reality.
There have been reports of active use of vilca by Wichi shamans, under the name hatáj. [34] Yopo: Anadenanthera peregrina: Beans: 5-MeO-DMT. Up to 7.4% bufotenin. [33] DMT Psychedelic: Archaeological evidence of insufflation use within the period 500-1000 AD, in northern Chile, has been reported. [35]
This is a list of investigational hallucinogens and entactogens, or hallucinogens and entactogens that are currently under formal development for clinical use but are not yet approved. [ 1 ] Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.
The research suggests that 7 of the 11 arrest variables were reduced with lifetime psilocybin use. Peyote use was found to reduce the odds of driving under the influence and vehicle theft. Lastly, mescaline use was found to reduce drug possession/sale. No other substances shared a positive relationship with reducing criminal behavior. [89]
Flying ointment is a hallucinogenic ointment said to have been used by witches in the practice of European witchcraft from at least as far back as the Early Modern period, when detailed recipes for such preparations were first recorded and when their usage spread to colonial North America.
The Harvard Psilocybin Project was a series of experiments in psychology conducted by Timothy Leary and Richard Alpert.The founding board of the project consisted of Leary, Aldous Huxley, David McClelland (Leary's and Alpert's superior at Harvard University), [21] Frank Barron, Ralph Metzner, and two graduate students who were working on a project with mescaline.
Leo E. Hollister (December 3, 1920 - December 19, 2000) [1] was an American professor emeritus of medicine, psychiatry and pharmacology. [ 2 ] Work on hallucinogens
PiHKAL: A Chemical Love Story is a book by Alexander Shulgin and Ann Shulgin published in 1991. [1] [2] The subject of the work is psychoactive phenethylamine chemical derivatives, notably those that act as psychedelics and/or empathogen-entactogens. The main title, PiHKAL, is an acronym that stands for "Phenethylamines I Have Known and Loved".