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A countercurrent system in the renal medulla provides the mechanism for generating a hypertonic interstitium, which allows the recovery of solute-free water from within the nephron and returning it to the venous vasculature when appropriate. Some diseases of the nephron predominantly affect either the glomeruli or the tubules.
Examples of substances reabsorbed are solute-free water, sodium, bicarbonate, glucose, and amino acids. Examples of substances secreted are hydrogen, ammonium, potassium and uric acid. The nephron is the structural and functional unit of the kidney. Each adult human kidney contains around 1 million nephrons, while a mouse kidney contains only ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 31 January 2025. List of organ systems in the human body Part of a series of lists about Human anatomy General Features Regions Variations Movements Systems Structures Arteries Bones Eponymous Foramina Glands endocrine exocrine Lymphatic vessels Nerves Organs Systems Veins Muscles Abductors Adductors ...
The glomerulus (pl.: glomeruli) is a network of small blood vessels (capillaries) known as a tuft, located at the beginning of a nephron in the kidney. Each of the two kidneys contains about one million nephrons. The tuft is structurally supported by the mesangium (the space between the blood vessels), composed of intraglomerular mesangial cells.
A renal corpuscle (or Malpighian body [1]) is the blood-filtering component of the nephron of the kidney. It consists of a glomerulus - a tuft of capillaries composed of endothelial cells - and a glomerular capsule known as Bowman's capsule .
Each nephron is located in both the cortex and the medulla. The most proximal part of the nephron is glomerulus, which is located in the cortex. [28] The nephrons of the mammalian kidneys have loops of Henle, which are the most efficient way to reabsorb water and produce concentrated urine to conserve water in the body. [12]
The nephron is composed of a renal corpuscle and a renal tubule. The renal corpuscle is a blood-filtering part of the nephron and is located in the cortex. The renal tubule extends from the renal corpuscle to the medulla into the loop of Henle and then returns back to the cortex. Finally, the renal tubule flows with its distal end into its ...
Diagram outlining movement of ions in nephron, with the collecting ducts on the right. The collecting duct system is the final component of the kidney to influence the body's electrolyte and fluid balance. In humans, the system accounts for 4–5% of the kidney's reabsorption of sodium and 5% of the kidney's reabsorption of water. At times of ...