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Retinyl palmitate, or vitamin A palmitate, is the ester of retinol and palmitic acid, with formula C 36 H 60 O 2. It is the most abundant form of vitamin A storage in animals. [2] An alternate spelling, retinol palmitate, which violates the -yl organic chemical naming convention for esters, is also frequently seen. [citation needed]
The causes are vitamin A deficiency during pregnancy, followed by low transfer of vitamin A during lactation and infant/child diets low in vitamin A or β-carotene. [ 22 ] [ 19 ] The prevalence of pre-school age children who are blind due to vitamin A deficiency is lower than expected from incidence of new cases only because childhood vitamin A ...
Retinol was discovered in 1909, isolated in 1931, and first made in 1947. [6] [7] It is on the World Health Organization's List of Essential Medicines. [8] Retinol is available as a generic medication and over the counter. [1] In 2021, vitamin A was the 298th most commonly prescribed medication in the United States, with more than 500,000 ...
Vitamin A in food exists either as preformed retinol – an active form of vitamin A – found in animal liver, dairy and egg products, and some fortified foods, or as provitamin A carotenoids, which are plant pigments digested into vitamin A after consuming carotenoid-rich plant foods, typically in red, orange, or yellow colors. [27]
World Health Organization "Recommendations for preformed vitamin A supplements for mothers during pregnancy" states that "health benefits are expected for the mother and her developing fetus with little risk of detriment to either, from a daily supplement not exceeding 10,000 IU vitamin A (3000mcg RE) at any time during pregnancy." Preformed ...
Assessing vitamin A status in persons with subtoxicity or toxicity is complicated because serum retinol concentrations are not sensitive indicators in this range of liver vitamin A reserves. [21] The range of serum retinol concentrations under normal conditions is 1–3 μmol/L and, because of homeostatic regulation, that range varies little ...
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Retinoic acid (simplified nomenclature for all-trans-retinoic acid) is a metabolite of vitamin A 1 (all-trans-retinol) that is required for embryonic development, male fertility, regulation of bone growth and immune function. [2] All-trans-retinoic acid is required for chordate animal development, which includes all higher animals from fish to ...