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  2. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    However, in clinical trials, high blood pressure was reported in just one percent of patients taking 2.5-milligram tadalafil and three percent of patients taking the 5-milligram dose.

  3. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

    www.aol.com/tadalafil-ultimate-guide-dosages...

    Tadalafil is available in several dosages, from a minimum dosage of 2.5mg (milligrams) all the way up to a 20mg per tablet, the maximum dose of tadalafil in 24 hours. Tadalafil 10mg: Typical ...

  4. Got Headaches from Viagra or Cialis? Here's Why & How to Treat It

    www.aol.com/got-headaches-viagra-cialis-heres...

    Headaches are a common side effect of ED medications such as sildenafil (the active ingredient in Viagra), tadalafil (Cialis) and vardenafil (Levitra), with about 25 percent of men prescribed ...

  5. Tadalafil - Wikipedia

    en.wikipedia.org/wiki/Tadalafil

    Tadalafil is not recommended in people taking nitrovasodilators such as nitroglycerin, as this may result in a serious drop in blood pressure. [8] Tadalafil is a PDE 5 inhibitor which increases blood flow to the penis. [8] It also dilates blood vessels in the lungs, which lowers the pulmonary artery pressure. [8]

  6. Therapeutic drug monitoring - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_drug_monitoring

    significant between-patient pharmacokinetic variability, making a standard dosage achieve different concentration levels among patients (while the drug disposition remains relatively stable in a given patient); narrow therapeutic window of the drug, which forbids giving high doses in all patients to ensure overall efficacy; [6]

  7. Effective dose (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Effective_dose_(pharmacology)

    The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...

  8. 4 Common ED Pills: Weighing the Pros & Cons of Each - AOL

    www.aol.com/4-common-ed-pills-weighing-141800609...

    Tadalafil has a half-life of 17.5 hours — it remains active in your body for far longer than other ED medications. A single dose of tadalafil can improve blood flow to your privates and make it ...

  9. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    PDE5 inhibitors are contraindicated within 24 hours (or 48 hours with tadalafil) of taking alpha-blockers, soluble guanylate cyclase stimulators, or nitrate medications such as isosorbide mononitrate or isosorbide dinitrate. [1] Concurrent use of these medications can lead to life-threatening low blood pressure. [5]