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  2. Adrenal cortex - Wikipedia

    en.wikipedia.org/wiki/Adrenal_cortex

    The adrenal cortex is the outer region and also the largest part of the adrenal gland. It is divided into three separate zones: zona glomerulosa, zona fasciculata and zona reticularis. Each zone is responsible for producing specific hormones. It is also a secondary site of androgen synthesis. [2]

  3. Adrenal gland - Wikipedia

    en.wikipedia.org/wiki/Adrenal_gland

    The adrenal cortex is the outermost layer of the adrenal gland. Within the cortex are three layers, called "zones". When viewed under a microscope each layer has a distinct appearance, and each has a different function. [13] The adrenal cortex is devoted to production of hormones, namely aldosterone, cortisol, and androgens. [14]

  4. Zona fasciculata - Wikipedia

    en.wikipedia.org/wiki/Zona_fasciculata

    Steroid-producing adrenal tumours and hyperplasia of the zona fasciculata result in excess cortisol production and are the cause for adrenal Cushing's syndrome. [1] The genetic disorder McCune–Albright syndrome can also present as Cushing's syndrome in affected patients. Adrenal gland (zona fasciculata layer).

  5. Zona reticularis - Wikipedia

    en.wikipedia.org/wiki/Zona_reticularis

    The zona reticularis (sometimes, reticulate zone) is the innermost layer of the adrenal cortex, lying deep to the zona fasciculata and superficial to the adrenal medulla. The cells are arranged cords that project in different directions giving a net-like appearance (L. reticulum - net).

  6. Adrenocortical hormone - Wikipedia

    en.wikipedia.org/wiki/Adrenocortical_hormone

    Adrenocortical hormones are divided into three classes by function: mineralocorticoids, glucocorticoids, and androgens. Mineralocorticoid hormones are synthesized in the outermost layer of the adrenal cortex known as the zona glomerulosa. [2] Their function is to regulate the concentration of electrolytes circulating in the blood. [1]

  7. Cortex (anatomy) - Wikipedia

    en.wikipedia.org/wiki/Cortex_(anatomy)

    The cerebral cortex, the outer layer of the cerebrum, plays a key role in memory, attention, perceptual awareness, thought, language, and consciousness. Cortical bone is the hard outer layer of bone; distinct from the spongy, inner cancellous bone tissue [2] Ovarian cortex is the outer layer of the ovary and contains the follicles.

  8. Zona glomerulosa - Wikipedia

    en.wikipedia.org/wiki/Zona_glomerulosa

    H & E staining of the adrenal cortex. The zona glomerulosa is the outermost layer, below the renal capsule (near the pointer) In response to increased potassium levels, renin or decreased blood flow to the kidneys, cells of the zona glomerulosa produce and secrete the mineralocorticoid aldosterone into the blood as part of the renin ...

  9. Adrenocorticotropic hormone - Wikipedia

    en.wikipedia.org/wiki/Adrenocorticotropic_hormone

    ACTH stimulates secretion of glucocorticoid steroid hormones from adrenal cortex cells, especially in the zona fasciculata of the adrenal glands. ACTH acts by binding to cell surface ACTH receptors, which are located primarily on adrenocortical cells of the adrenal cortex. The ACTH receptor is a seven-membrane-spanning G protein-coupled ...