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Antiretroviral drugs are used to manage HIV/AIDS. Multiple antiretroviral drugs are often combined into a single pill in order to reduce pill burden. Some of these combinations are complete single-tablet regimens; the others must be combined with additional pills to make a treatment regimen.
Furthermore, the PARTNER study, [43] which ran from 2010 to 2014, enrolled 1166 serodiscordant couples (where one partner is HIV positive and the other is negative) in a study that found that the estimated rate of transmission through any condomless sex with the HIV-positive partner taking ART with an HIV load less than 200 copies/ml was zero. [43]
Heterosexual men or women who do not regularly use condoms during sex with partners of unknown HIV status who are substantial risk; Injection of drugs in the last six months with sharing of equipment; Serodiscordant heterosexual and homosexual partners, where one partner is HIV-positive and the other HIV-negative
The HIV Prevention Trials Network conducted a clinical trial, HPTN 052, that analyzed the effectiveness of antiretroviral drugs on the HIV-1 virus. 1,783 HIV sero-discordant couples, or couples that consist of an HIV-positive individual and an HIV-negative partner, from nine different countries were a part of the study, 97% of the couples being ...
An HIV-positive sexual partner (especially if they have an unknown or detectable viral load); A bacterial sexually transmitted infection (STI) in the past 6 months. Patients reporting injection drug use within the last 6 months and any of the following: An HIV-positive injecting partner; Shared injection equipment.
These changes minimize interactions between drugs, lower clearance, and increase solubility. Bictegravir was found to be less drug resistant than other drugs in the same class. [16] Emtricitabine (FTC) is a nucleoside reverse transcriptase inhibitor (NRTI) that is a synthetic fluoro derivative of thiacytidine. Within the cell, emtricitabine ...
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