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Sirolimus is a relatively new medical therapy for the treatment of vascular malformations [25] in recent years, sirolimus has emerged as a new medical treatment option for both vascular tumors and vascular malformations, as a mammalian target of rapamycin (mTOR), capable of integrating signals from the PI3K/AKT pathway to coordinate proper cell ...
The post Why I Started and Stopped Taking the “Anti-Aging” Drug Rapamycin appeared first on AGEIST. I am a healthy sixty-one-year-old man. Addressing my health, fitness, and longevity has been ...
Everolimus, sold under the brand name Afinitor among others, is a medication used as an immunosuppressant to prevent rejection of organ transplants [10] and as a targeted therapy in the treatment of renal cell cancer and other tumours. [11] This compound also has a use in cardiovascular drug-eluting stent technologies to inhibit restenosis.
mTOR inhibitors are a class of drugs used to treat several human diseases, including cancer, autoimmune diseases, and neurodegeneration. They function by inhibiting the mammalian target of rapamycin (mTOR) (also known as the mechanistic target of rapamycin), which is a serine/threonine-specific protein kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K) related kinases ...
While not approved as anti-aging treatments, these drugs score the highest on his 12-point scale assessing their longevity potential. “Some of those drugs have been decreasing hospitalization, ...
A 2007 review on the use of human growth hormone as an anti-aging treatment in healthy elderly people published in the Annals of Internal Medicine concluded the risks of HGH significantly outweigh the benefits, noted soft tissue edema as a common side effect and found no evidence that the hormone prolongs life. [36]