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PCOS is the primary cause of anovulation, which results in female infertility. [5] The induction of mono-ovulatory cycles can restore fertility. [6] The oral drug clomiphene citrate (CC) is the first-line treatment for PCOS-related infertility, yet one-fifth of women are resistant to the drug and fail to ovulate. [7]
For those who after weight loss still are anovulatory or for anovulatory lean women, ovulation induction to reverse the anovulation is the principal treatment used to help infertility in PCOS. Letrozole and Clomiphene citrate are the first-line treatment in subfertile anovulatory patients with PCOS. [12]
Combined oral contraceptives are especially effective and used as the first line of treatment to reduce acne and hirsutism and regulate the menstrual cycle. This is especially the case in adolescents. [109] Metformin, GLP-1, and anti-androgens may also help. [12] Other typical acne treatments and hair removal techniques may be used. [12]
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Treatment for management of anovulation due to PCOS is multifaceted, including weight reduction, ovulation induction agents, insulin-sensitizing agents, gonadotrophins and ovarian drilling. In PCOS patients with overweight or obesity, weight loss is first line treatment.
One in 10 women are thought to suffer from PCOS. For premium support please call: 800-290-4726 more ways to reach us
Lauren lost weight amid treatment for her PCOS. In 2022, fans speculated that Lauren had weight loss surgery after she had noticeably slimmed down. So, Lauren hopped on Instagram to set the record ...
Dopamine agonists for infertility treatment are commonly administered to hyperprolactinemic anovulation patients. Both bromocriptine and cabergoline are the first-line dopamine agonist in hyperprolactinemia treatment. [46] Cabergoline is currently more preferred than bromocrptine due to its higher efficacy and fewer side effects like nausea. [53]