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Folic acid supplementation is recommended prior to conception, to prevent development of spina bifida and other neural tube defects. It should be taken as at least 0.4 mg/day throughout the first trimester of pregnancy, 0.6 mg/day through the pregnancy, and 0.5 mg/day while breastfeeding in addition to eating foods rich in folic acid such as ...
[7] [105] After the discovery of the link between insufficient folic acid and neural tube defects, governments and health organizations worldwide made recommendations concerning folic acid supplementation for women intending to become pregnant. Because the neural tube closes in the first four weeks of gestation, often before many women even ...
Treatment may include dietary changes and folic acid supplements. [1] Dietary changes including eating foods high in folate such as, fruits and green leafy vegetables can help. [1] Prevention is recommended for pregnant women or those who are planning a pregnancy. [1] Folate deficiency is very rare in countries with folic acid fortification ...
The reason for this last recommendation is that nine in 10 women have such a low blood level of folic acid that they risk having a baby with a neural tube defect (NTD) – a serious birth defect ...
The recommendation to start folic acid before conception is supported by a meta-analysis of 41 studies, but is beneficial after conception as well. [ 2 ] Often prenatal vitamins also have a reduced dosage of vitamins that may be detrimental to the fetus when taken in high doses (such as vitamin A ).
Anemias due to other deficiencies such as folic acid or vitamin B12 can also be treated with supplementation as well; dose may vary based on level of deficiency. [32] Other forms of anemias, such as inherited or acquired anemias prior to pregnancy, will require continuous management during pregnancy as well. [29]