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The artificial sweetener aspartame has been the subject of several controversies since its initial approval by the U.S. Food and Drug Administration (FDA) in 1974. The FDA approval of aspartame was highly contested, beginning with suspicions of its involvement in brain cancer, [1] alleging that the quality of the initial research supporting its safety was inadequate and flawed, and that ...
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"Aspartame is one of the most studied food additives in the human food supply. FDA scientists do not have safety concerns when aspartame is used under the approved conditions,” the FDA said in a ...
In July 2023, after reviewing research on humans and animals, the World Health Organization (WHO) added aspartame, a common ingredient in diet soda, to a list of ingredients that are “possibly ...
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Aspartame is an artificial non-saccharide sweetener commonly used as a sugar substitute in foods and beverages. [4] 200 times sweeter than sucrose, it is a methyl ester of the aspartic acid/phenylalanine dipeptide with brand names NutraSweet, Equal, and Canderel. [4]
The FDA did not agree, noting aspartame is “one of the most studied food additives in the human food supply." There's mounting evidence suggesting artificial sweeteners and sugar alcohols may be ...
A 2016 review described the relationship between non-nutritive sweeteners as inconclusive. [46] A 2020 Cochrane systematic review compared several non-nutritive sweeteners to sugar, placebo and a nutritive low-calorie sweetener , but the results were unclear for effects on HbA1c, body weight and adverse events. [47]