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There is little modern clinical research on Dioscorea villosa, and the one study of a wild yam-containing cream for menopausal symptoms failed to find any value from this therapy. [18] According to the American Cancer Society , there is no evidence to support wild yam or diosgenin being either safe or effective in humans.
Women often use hormone therapy to relieve hot flashes and other menopause symptoms — and new research suggests patches or creams may be safer for their blood pressure than pills. High blood ...
Diosgenin, a phytosteroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted from the tubers of Dioscorea wild yam species, such as the Kokoro. It is also present in smaller amounts in a number of other species.
[8] [irrelevant citation] Wild yams are an important crop, as they have been used to prevent menstrual cramps, stomach cramps, and general pain for centuries. During the 1950s scientists found that the roots of wild yams contained diosgenin which is a plant-based estrogen; diosgenin is hypothesized to aid in chemical defense against herbivores.
Hot flashes and night sweats happen to most women—yet there’s still so much we don’t know. But science is starting to catch up.
Creams. Conjugated estrogens (Premarin) – 0.625 mg/g (0.0625%) ... For Women: Menopause—Medicines to Help You – U.S. Food and Drug Administration
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