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Preoperative PVE is a very well tolerated procedure with extremely low mortality rates (0.1 percent) and technical failure rates (0.4 percent). [3] Complication rates from the procedure are low as well (2–3 percent) and include portal vein thrombosis, liver infarction, necrosis, infection, pneumothorax, and other risks as listed above. [3]
Surgical resection is associated with a greater than 60% survival rate at 5 years and a recurrence rate greater than 70%. [6] Surgical removal of the tumor is associated with better cancer prognosis, but only 5–15% of patients are suitable for surgical resection due to the extent of disease or poor liver function. [ 58 ]
Surgical resection of liver metastases from colorectal cancer has been found to be safe and cost-effective. [3] Reports from several large retrospective patient series suggest that it has a 5-year overall survival rate (5y OSR) averaging 30 to 40% and a 10y OSR around 16%, [ 1 ] [ 2 ] [ 4 ] [ 5 ] whereas the highest 5y OSR for modern ...
Resection is an option in cholangiocarcinoma, but fewer than 30% of cases of cholangiocarcinoma are resectable at diagnosis. The reason the majority of intrahepatic cholangiocarcinomas are not able to be surgically removed is because there are often multiple focal tumors within the liver. [70] After surgery, recurrence rates are up to 60%.
Hepatectomy is the surgical resection (removal of all or part) of the liver. While the term is often employed for the removal of the liver from a liver transplant donor, this article will focus on partial resections of hepatic tissue and hepatoportoenterostomy .
Even when surgery is successful the 5-year survival is typically less than 50%. [6] Cholangiocarcinoma is rare in the Western world, with estimates of it occurring in 0.5–2 people per 100,000 per year. [1] [6] Rates are higher in Southeast Asia where liver flukes are common. [5] Rates in parts of Thailand are 60 per 100,000 per year. [5]
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