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There are concerns that injecting it into a joint can cause problems with the cartilage. [9] It appears to be generally safe for use in pregnancy. [8] A lower dose may be required in those with liver problems. [8] It is generally safe to use in those allergic to tetracaine or benzocaine. [9] Lidocaine is an antiarrhythmic medication of the ...
The lidocaine patch is proven to reduce acute or short-term pain after surgeries or procedures at rest. There has been no proven decreased opioid use from lidocaine patches. There has been no research regarding specific procedures and the effects of transdermal lidocaine, but the efficacy of lidocaine is considered minor. [8]
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.
Kidney ischemia [1] is a disease with a high morbidity and mortality rate. [2] Blood vessels shrink and undergo apoptosis which results in poor blood flow in the kidneys. More complications happen when failure of the kidney functions result in toxicity in various parts of the body which may cause septic shock, hypovolemia, and a need for surgery. [3]
Diabetic nephropathy, also known as diabetic kidney disease, [5] is the chronic loss of kidney function occurring in those with diabetes mellitus. Diabetic nephropathy is the leading causes of chronic kidney disease (CKD) and end-stage renal disease (ESRD) globally. The triad of protein leaking into the urine (proteinuria or albuminuria ...
[6] [4] [5] Symptoms may include muscle pains, weakness, vomiting, and confusion. [3] [4] There may be tea-colored urine or an irregular heartbeat. [3] [5] Some of the muscle breakdown products, such as the protein myoglobin, are harmful to the kidneys and can cause acute kidney injury. [7] [3]