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Jarisch–Herxheimer reaction in a person with syphilis and human immunodeficiency virus [71] One of the potential side effects of treatment is the Jarisch–Herxheimer reaction . [ 3 ] It frequently starts within one hour and lasts for 24 hours, with symptoms of fever, muscle pains, headache, and a fast heart rate . [ 3 ]
The mumps virus lives in the upper respiratory tract and spreads through direct contact with saliva. [77] Prior to widespread vaccination programs, it was a common childhood disease. Mumps is generally not serious in children, but in adults, where sperm have matured in the testis, it can cause more severe complications, such as infertility.
Sertoli cell-only syndrome (SCOS), also known as germ cell aplasia, is defined by azoospermia where the testicular seminiferous tubules are lined solely with sertoli cells. [2] Sertoli cells contribute to the formation of the blood-testis barrier and aid in sperm generation.
The history of syphilis has been well studied, but the exact origin of the disease was the source of debate until archaeological and genetic evidence showed conclusively it originated in the Americas.
The lower part persists as the gubernaculum testis ("scrotal ligament"). This ligament secures the testis to the most inferior portion of the scrotum, tethering it in place and limiting the degree to which the testis can move within the scrotum. Cryptorchidism (undescended testes) are observed in INSL3-null male mice.
Gummas have a firm, necrotic center surrounded by inflamed tissue, which forms an amorphous proteinaceous mass. The center may become partly hyalinized.These central regions begin to die through coagulative necrosis, though they also retain some of the structural characteristics of previously normal tissues, enabling a distinction from the granulomas of tuberculosis where caseous necrosis ...
Testicular cancer is most common in males between the age 20–34 years old, and can appear as soon as the age of 15 years old. It is important to start STE at a young age, to detect any possible signs for testicular cancer. [7] A testicular self-examination can be done in front of a mirror to look at the entire surface.
The ectopic testis can be in the perineal region, the opposite side of the scrotum, the suprapubic region, the femoral region, or the superficial inguinal pouch. [1]The ectopic testis is initially normal, but if it is ignored after childhood, it may become small and soft, with spermatogenesis arresting and interstitial cell proliferation occurring.