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Dermatosis papulosa nigra. Dermatosis papulosa nigra (DPN) is a condition of many small, benign skin lesions on the face, a condition generally presenting on dark-skinned individuals. [1]: 638–9 DPN is extremely common, affecting up to 30% of Black people in the US. [2] From a histological perspective, DPN resembles seborrheic keratoses. [3]
Melanocytic nevus. A melanocytic nevus (also known as nevocytic nevus, nevus-cell nevus, and commonly as a mole) [1][2] is usually a noncancerous condition of pigment-producing skin cells. It is a type of melanocytic tumor that contains nevus cells. [2] A mole can be either subdermal (under the skin) or a pigmented growth on the skin, formed ...
9. ] Cutaneous squamous-cell carcinoma (cSCC), also known as squamous-cell carcinoma of the skin or squamous-cell skin cancer, is one of the three principal types of skin cancer, alongside basal-cell carcinoma and melanoma. [10] cSCC typically presents as a hard lump with a scaly surface, though it may also present as an ulcer. [1]
A study examining over 4,000 biopsied skin lesions identified clinically as seborrheic keratoses showed 3.1% were malignancies. Two-thirds of those were squamous cell carcinoma. [11] To date, the gold standard in the diagnosis of seborrheic keratosis is represented by the histolopathologic analysis of a skin biopsy. [12]
Surgery to remove the basal-cell carcinoma affected area and the surrounding skin is thought to be the most effective treatment. [40] A disadvantage with standard surgical excision is a reported higher recurrence rate of basal-cell cancers of the face, [41] especially around the eyelids, [42] nose, and facial structures. [43]
Keratoacanthoma is commonly found on sun-exposed skin, often face, forearms and hands. [2] [3] It is rarely found at a mucocutaneous junction or on mucous membranes. [2] Keratoacanthoma may be difficult to distinguish visually from a skin cancer. [4] Under the microscope, keratoacanthoma very closely resembles squamous cell carcinoma. In order ...
Lupus pernio is a chronic raised indurated (hardened) lesion of the skin, often purplish in color. It is seen on the nose, ears, cheeks, lips, and forehead. It is pathognomonic of sarcoidosis. [1]: 701 The name "lupus pernio" is a misnomer, as microscopically this disease shows granulomatous infiltration and does not have features of either ...
Spitz nevus. A Spitz nevus is a benign skin lesion. A type of melanocytic nevus, it affects the epidermis and dermis. [1] It is also known as an epithelioid and spindle-cell nevus, [2] and misleadingly as a benign juvenile melanoma, [2]: 691 and Spitz's juvenile melanoma[3]). The name juvenile melanoma is generally no longer used as it is ...