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However, the olfactory sensory neurons to which olfactory bulb neurons are connected are also distributed across the receptor sheet (the olfactory epithelium) depending on their chemical preferences. Locations on the olfactory epithelium and the olfactory bulb are correlated [ 8 ] so, as with other sensory systems, the topographic map in the ...
Humans have between 10 and 20 million olfactory receptor neurons (ORNs). [3] In vertebrates, ORNs are bipolar neurons with dendrites facing the external surface of the cribriform plate with axons that pass through the cribriform foramina with terminal end at olfactory bulbs. The ORNs are located in the olfactory epithelium in the
Unique to the olfactory and gustatory systems, at least in mammals, is the implementation of both peripheral and central mechanisms of action. [clarification needed] The peripheral mechanisms involve olfactory receptor neurons which transduce a chemical signal along the olfactory nerve, which terminates in the olfactory bulb.
The peripheral olfactory system consists mainly of the nostrils, ethmoid bone, nasal cavity, and the olfactory epithelium (layers of thin tissue covered in mucus that line the nasal cavity). The primary components of the layers of epithelial tissue are the mucous membranes, olfactory glands, olfactory neurons, and nerve fibers of the olfactory ...
Once the olfactory sensory neurons differentiate, they express odorant receptors, which transduce odorant information from the environment to the central nervous system and aids in the development of the odorant map. [20] The differentiated olfactory sensory neurons extend pioneering axons, which follow guidance cues released by the underlying ...
A sensory map is an area of the brain which responds to sensory stimulation, and are spatially organized according to some feature of the sensory stimulation. In some cases the sensory map is simply a topographic representation of a sensory surface such as the skin, cochlea, or retina. In other cases it represents other stimulus properties ...
Olfactory neurons utilize a feedback system from the levels of Ca 2+ ions to activate its adaptation to prolonged smells. Due to the fact that the olfactory signal transduction uses a second messenger transduction system, the mechanism of adaptation includes several factors that mostly include CaMK or calmodulin bound to Ca 2+ ions.
Retinal neurons and target cells had identification tags in the form of chemical gradients so that the projection of neurons would be orderly. For a topographic map of the visual world, the map first forms during neural development via molecular signals, such as chemospecific matching between molecular gradients. [14]