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It is located at the junction of the urethra with the urinary bladder and is continuous with the detrusor muscle, [1] [2] but anatomically and functionally fully independent from it. [3] It is composed of smooth muscle, so it is under the control of the autonomic nervous system, specifically the sympathetic nervous system.
The sympathetic nervous system (SNS or SANS, sympathetic autonomic nervous system, to differentiate it from the somatic nervous system) is one of the three divisions of the autonomic nervous system, the others being the parasympathetic nervous system and the enteric nervous system.
The main organs involved in urination are the urinary bladder and the urethra.The smooth muscle of the bladder, known as the detrusor, is innervated by sympathetic nervous system fibers from the lumbar spinal cord and parasympathetic fibers from the sacral spinal cord. [6]
The bladder receives both sensory and motor supply from sympathetic and the parasympathetic nervous systems. [11] The motor supply from both sympathetic fibers, most of which arise from the superior and inferior hypogastric plexuses and nerves, and from parasympathetic fibers, which come from the pelvic splanchnic nerves. [12]
The internal sphincter, formed by the involuntary smooth muscles lining the bladder neck and urethra, receives its nerve supply by the sympathetic division of the autonomic nervous system. [6] The internal sphincter is present both in males and females. [7] [8] [9]
The bladder also contains β 3 adrenergic receptors, and pharmacological agonists of this receptor are used to treat overactive bladder. The mucosa of the urinary bladder may herniate through the detrusor muscle. [6] This is most often an acquired condition due to high pressure in the urinary bladder, damage, or existing connective tissue ...
Autonomic nervous system, showing splanchnic nerves in middle, and the vagus nerve as "X" in blue. The heart and organs below in list to right are regarded as viscera. The autonomic nervous system has been classically divided into the sympathetic nervous system and parasympathetic nervous system only (i.e., exclusively motor).
The autonomic nervous system is a component of the peripheral nervous system and comprises two branches: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PSNS). The SNS controls the more active responses, such as increasing heart rate and blood pressure.