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Cholera has been nicknamed the "blue death" [22] because a person's skin may turn bluish-gray from extreme loss of fluids. [23] Fever is rare and should raise suspicion for secondary infection. Patients can be lethargic and might have sunken eyes, dry mouth, cold clammy skin, or wrinkled hands and feet.
The major shortcoming of most patient portals is their linkage to a single health organization. If a patient uses more than one organization for healthcare, the patient typically needs to log on to each organization's portal to access information. This results in a fragmented view of individual patient data. [3]
[8] [2] As of December 2021, Mayo Clinic Health System facilities served 600,000 patients across its operating regions. [19] After combining its Albert Lea and Austin hospitals into a single entity with two campuses in 2013, Mayo Clinic Health System announced in 2017 that it would consolidate inpatient services to the Austin campus.
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In 2011, Mayo Clinic launched the Mayo Clinic Care Network, a collection of facilities with access to Mayo Clinic protocols and experts. [59] In November 2019, the Mayo Clinic, in a joint partnership with SEHA Abu Dhabi Health Services Co, invested $50 million into a 741-bed hospital in the United Arab Emirates for a 25% stake. [60] [61] [62]
Cholera toxin mechanism. Cholera toxin (also known as choleragen and sometimes abbreviated to CTX, Ctx or CT) is an AB5 multimeric protein complex secreted by the bacterium Vibrio cholerae. [1] [2] CTX is responsible for the massive, watery diarrhea characteristic of cholera infection. [3] It is a member of the heat-labile enterotoxin family.
Cholera infections are most commonly acquired from drinking water in which V. cholerae is found naturally or into which it has been introduced from the feces of an infected person. Cholera is most likely to be found and spread in places with inadequate water treatment, poor sanitation, and inadequate hygiene.