Search results
Results From The WOW.Com Content Network
Elevated troponin levels are prognostically important in many of the conditions in which they are used for diagnosis. [ 36 ] In a community-based cohort study indicating the importance of silent cardiac damage, troponin I has been shown to predict mortality and first coronary heart disease event in men free from cardiovascular disease at ...
Test Sensitivity and specificity Approximate peak Description Troponin test: The most sensitive and specific test for myocardial damage. Because it has increased specificity compared with CK-MB, troponin is composed of 3 proteins- Troponin C, Cardic troponin I, and Cardiac troponin T. Troponin I especially has a high affinity for myocardial injury.
Troponin I is a biomarker that responds to treatment interventions. Reductions in troponin I levels proved to reduce the risk of future CVD. [23] [24] [25] High sensitive troponin I used as a screening tool to assess a person's cardiovascular risk and has the potential to reduce the growing cost burden of the healthcare system. [26]
Troponin T binds to tropomyosin and helps position it on actin, [2] and together with the rest of the troponin complex, modulates contraction of striated muscle. [3] The cardiac subtype of troponin T is especially useful in the laboratory diagnosis of heart attack because it is released into the blood-stream when damage to heart muscle occurs ...
The level of the troponin, as well as a change over time, are useful in measuring and diagnosing or excluding myocardial infarctions, and the diagnostic accuracy of troponin testing is improving over time. [72] One high-sensitivity cardiac troponin can rule out a heart attack as long as the ECG is normal. [83] [84]
Cardiac sarcomere structure, featuring troponin T. Cardiac muscle troponin T (cTnT) is a protein that in humans is encoded by the TNNT2 gene. [5] [6] Cardiac TnT is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration.
Psychologists Arthur and Elaine Aron are known for research behind the “36 Questions That Lead to Love.” They share how their relationship has lasted over 50 years.
A mnemonic can be used for some causes of ST depression, namely DEPRESSED ST: [citation needed]. D - Drooping valve (mitral valve prolapse) E - Enlargement of the left ventricle P - Potassium loss R - Reciprocal ST depression (e.g. inferior wall MI) E - Encephalon hemorrhage S - Subendocardial infarct S - Subendocardial ischemia E - Embolism (pulmonary) D - Dilated cardiomyopathy S - Shock T ...