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Brian Wallach (born October 9, 1980) is an American businessman, lawyer, and amyotrophic lateral sclerosis (ALS) research and patient advocate. He became known for his activism after being diagnosed with ALS in 2017. [1] Since then, Wallach has founded a nonprofit, I AM ALS, and a telemedicine company, Synapticure.
ALS is the most common form of the motor neuron diseases. [8] ALS often presents in its early stages with gradual muscle stiffness, twitches, weakness, and wasting. [3] Motor neuron loss typically continues until the abilities to eat, speak, move, and, lastly, breathe are all lost. [3]
He was awarded the Congressional Gold Medal for his contributions to ALS awareness. Activist Brian Wallach's advocacy through his foundation I AM ALS saw the Accelerating Access to Critical Therapies for ALS Act signed into law by President Joe Biden in 2021. Jason Becker (born 1969), American musician, songwriter and composer. [1]
[4] [5] ALS has an oligogenic mode of inheritance, meaning that mutations in two or more genes are required to cause disease. [6] C9orf72 is the most common gene associated with ALS, causing 40% of familial cases of ALS, as well as a small percentage of sporadic cases; [7] it also causes about 25% of familial cases of frontotemporal dementia. [6]
The ALS Association is an American nonprofit organization that funds global amyotrophic lateral sclerosis (ALS) research, provides care services and programs to people affected by ALS through its nationwide network of clinical care centers, and works with ALS advocates around the country for state and federal policies that serve people living with amyotrophic lateral sclerosis (ALS), also ...
Articles relating to amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or Lou Gehrig's disease. It is a specific disease which causes the death of neurons controlling voluntary muscles. ALS is characterized by stiff muscles, muscle twitching, and gradually worsening weakness due to muscles decreasing in size.
Familial ALS is the most studied; however, a new technique that was recently introduced is the use of induced pluripotent stem cells (iPSC). [2] In this study the researcher can isolate skin fibroblast from a patient with familial or sporadic ALS and reprogram them into motor neuron to study ALS. [ 2 ]
An advanced life support paramedic unit of Palm Beach County Fire-Rescue used for EMS in Palm Beach County, Florida.. Advanced Life Support (ALS) is a set of life saving protocols and skills that extend basic life support to further support the circulation and provide an open airway and adequate ventilation (breathing).