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MGUS is a relatively stable condition afflicting 3% of people aged 50 and 5% of people aged 70; it progresses to multiple myeloma at a rate of 0.5–1% cases per year; smoldering multiple myeloma does so at a rate of 10% per year for the first 5 years, but then falls off sharply to 3% per year for the next 5 years and thereafter to 1% per year.
Smouldering myeloma is a disease classified as intermediate in a spectrum of step-wise progressive diseases termed plasma cell dyscrasias.In this spectrum of diseases, a clone of plasma cells secreting monoclonal paraprotein (also termed myeloma protein or M protein) causes the relatively benign disease of monoclonal gammopathy of undetermined significance.
multiple myeloma Reduced production ( hypogammaglobulinemia ), as well as increased protein loss ( nephrotic syndrome , protein-losing enteropathy ), can cause hypoproteinemia. To determine the reason behind the lower serum total protein, a serum protein electrophoresis ought to be carried out.
People who died from the plasma cell cancer multiple myeloma. Myeloma is a form of what is commonly known as "blood cancer". See: Category:People with multiple myeloma for those currently living with the disease.
The causes listed are relatively immediate medical causes, but the ultimate cause of death might be described differently. For example, tobacco smoking often causes lung disease or cancer, and alcohol use disorder can cause liver failure or a motor vehicle accident.
The veteran reporter, diagnosed with multiple myeloma in 2014 and retired after 55 years in 2021, told his former “Today” show co-anchor Jane Pauley in an upcoming interview that his fight ...