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Cataplexy without narcolepsy is rare and the cause is unknown. The term cataplexy originates from the Greek κατά ( kata , meaning "down"), and πλῆξις ( plēxis , meaning "strike") [ 4 ] and it was first used around 1880 in German physiology literature to describe the phenomenon of tonic immobility also known as " playing possum " (in ...
The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1] People with narcolepsy tend to sleep about the same number of hours per day as people without it, but the quality of sleep is typically compromised. [1]
This is because, by definition, type 2 narcolepsy is narcolepsy without the symptom of cataplexy. This means that while type 1 narcolepsy (narcolepsy with cataplexy) has a defined pathophysiology, type 2 narcolepsy is a term to describe narcolepsy arising from other means. [2] [6]
Experts say cataplexy, which is a loss of muscle tone, often accompanies narcolepsy. In the video, Sarah was working on a traditional Japanese dance to send to a choreographer friend. "I realized ...
The prevalence of narcolepsy (with cataplexy) is estimated between 1/3,300 and 1/5,000. [47] Although the true prevalence of IH is unknown, it is estimated at 1/10,000 to 1/25,000 for the long sleep form and 1/11,000 to 1/100,000 without long sleep. [48]
Orexin (/ ɒ ˈ r ɛ k s ɪ n /), also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. [5] It exists in the forms of orexin-A and orexin-B.The most common form of narcolepsy, type 1, in which the individual experiences brief losses of muscle tone ("drop attacks" or cataplexy), is caused by a lack of orexin in the brain due to destruction of the cells ...