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An immature teratoma is a teratoma that contains anaplastic immature elements, and is often synonymous with malignant teratoma. [1] A teratoma is a tumor of germ cell origin, containing tissues from more than one germ cell line, [2] [3] [4] It can be ovarian or testicular in its origin. [4] and are almost always benign. [5]
Ovarian tumors by incidence and risk of ovarian cancer, with mature cystic teratoma at bottom and immature teratoma at right. [55] Embryonal teratomas most commonly occur in the sacrococcygeal region; sacrococcygeal teratoma is the single most common tumor found in newborn humans.
Teratoma are most common germ cell tumor of ovary. Teratomas can be divided into two types: mature teratoma (benign) and immature teratoma (malignant). Immature teratomas contain immature or embryonic tissue which significantly differentiates them from mature teratomas as they carry dermoid cysts. [5]
Polyembryomas, the most immature form of teratoma and very rare ovarian tumors, are histologically characterized by having several embryo-like bodies with structures resembling a germ disk, yolk sac, and amniotic sac. Syncytiotrophoblast giant cells also occur in polyembryomas. [32]
Mature cystic teratoma: 46.0%: 0.17% to 2% [6] Cystic, with elements of all 3 germ layers (endoderm, mesoderm and ectoderm). [7] Hair follicles. Immature teratoma: 2.5%: 100%: A teratoma that contains anaplastic immature elements, and is often synonymous with malignant teratoma. [8] Other germ cell tumors 3.0%
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pelvis, particularly sacrococcygeal teratoma; In females, GCTs account for 30% of ovarian tumors, but only 1 to 3% of ovarian cancers in North America. In younger women, they are more common, thus in patients under the age of 21, 60% of ovarian tumors are of the germ-cell type, and up to one-third are malignant.