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Serious side effects may include angioedema, low blood sugar, kidney problems, pancreatitis, and joint pain. [8] Whether use in pregnancy or breastfeeding is safe is unclear. [ 10 ] It is in the dipeptidyl peptidase-4 (DPP-4) inhibitor class and works by increasing the production of insulin and decreasing the production of glucagon by the pancreas.
The combination of protein and fiber can help slow digestion, promote steadier blood sugar levels and reduce the risk of post-meal glucose spikes. 3. Keep Caffeine in Check.
In the United States, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. [5] [6]In the European Union, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in people with type 2 diabetes; in combination with a sulfonylurea as an adjunct to diet and exercise "in people ...
The screening involves getting an A1C test, also known as a hemoglobin A1C test, to measure your average blood sugar level over the past 90 days. Dr. Peterson says this blood test is used to ...
Glucagon increases blood glucose levels, and DPP-4 inhibitors reduce glucagon and blood glucose levels. The mechanism of DPP-4 inhibitors is to increase incretin levels ( GLP-1 and GIP ), [ 2 ] [ 3 ] [ 4 ] which inhibit glucagon release, which in turn increases insulin secretion, decreases gastric emptying, and decreases blood glucose levels.
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