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Central pain syndrome, also known as central neuropathic pain, [1] is a neurological condition consisting of constant moderate to severe pain due to damage to the central nervous system (CNS) which causes a sensitization of the pain system. [2] [3] The extent of pain and the areas affected are related to the cause of the injury. [4]
Explanatory model of chronic pain. Chronic pain is defined as reoccurring or persistent pain lasting more than 3 months. [1] The International Association for the Study of Pain (IASP) defines pain as "An unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage". [2]
Complex regional pain syndrome, Diffuse idiopathic pain (Also known as juvenile fibromyalgia), Intermittent amplified pain, Localized amplified pain [1] [2] Causes: Psychological trauma, physical injury, illness [1] [6] Risk factors: Asthma, autoimmune diseases, [1] arthritis, myositis, Ehlers-Danlos syndrome, rheumatologic diseases, being ...
Arthritis is predominantly a disease of the elderly, but children can also be affected by the disease. [105] Arthritis is more common in women than men at all ages and affects all races, ethnic groups and cultures. In the United States, a CDC survey based on data from 2013 to 2015 showed 54.4 million (22.7%) adults had self-reported doctor ...
Nociplastic pain (or central sensitization) is less understood and is the common explanation of the pain experienced in fibromyalgia. [13] [16] [73] Because the three forms of pain can overlap, fibromyalgia patients may experience nociceptive (e.g., rheumatic illnesses) and neuropathic (e.g., small fiber neuropathy) pain, in addition to ...
Myofascial pain syndrome (MPS) is commonly confused with fibromyalgia (FM) as their presentation is similar. However, fibromyalgia is typically associated with fatigue, depression and cognitive dysfunction. The anatomic distribution and characteristic of the pain also differ.
Nociplastic pain is a longterm complex pain, one of three mechanisms of pain, defined by the International Association for the Study of Pain as "pain that arises from altered nociception despite no clear evidence of actual or threatened tissue damage causing the activation of peripheral nociceptors or evidence for disease or lesion of the somatosensory system causing the pain". [2]
Allodynia is a clinical feature of many painful conditions, such as neuropathies, [4] complex regional pain syndrome, postherpetic neuralgia, fibromyalgia, and migraine. Allodynia may also be caused by some populations of stem cells used to treat nerve damage including spinal cord injury. [5]