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  2. Daratumumab - Wikipedia

    en.wikipedia.org/wiki/Daratumumab

    Treatment of multiple myeloma with daratumumab potentially increases the patient's susceptibility to bacterial and viral infections, due to the killing of natural killer cells (which are the main innate immune system defense against virus). [16] Daratumumab frequently causes human cytomegalovirus (CMV) reactivation by an unknown mechanism. [17]

  3. Rating scales for depression - Wikipedia

    en.wikipedia.org/wiki/Rating_scales_for_depression

    Some depression rating scales are completed by patients. The Beck Depression Inventory, for example, is a 21-question self-report inventory that covers symptoms such as irritability, fatigue, weight loss, lack of interest in sex, and feelings of guilt, hopelessness or fear of being punished. [11]

  4. PHQ-9 - Wikipedia

    en.wikipedia.org/wiki/PHQ-9

    It cannot be used to make an actual diagnosis. Only a trained clinician can do that. For example, a trained clinician can determine if the symptoms can be better explained by substance use or another medical or psychiatric condition. Clinicians, however, may use the PHQ-9 to evaluate the efficacy of treatments for depression.

  5. Management of depression - Wikipedia

    en.wikipedia.org/wiki/Management_of_depression

    The risk factors [110] for treatment resistant depression are: the duration of the episode of depression, severity of the episode, if bipolar, lack of improvement in symptoms within the first couple of treatment weeks, anxious or avoidant and borderline comorbidity and old age. Treatment resistant depression is best handled with a combination ...

  6. Daratumumab/hyaluronidase - Wikipedia

    en.wikipedia.org/wiki/Daratumumab/hyaluronidase

    It was approved for use in the United States in May 2020. [2] [7] [8]Efficacy of daratumumab and hyaluronidase-fihji (monotherapy) was evaluated in the COLUMBA trial (NCT03277105), an open-label non-inferiority trial randomizing 263 participants to daratumumab and hyaluronidase-fihj and 259 to intravenous daratumumab (daratumumab IV). [2]

  7. Taking This Daily Vitamin Could Slash Dementia Risk By 40% ...

    www.aol.com/taking-daily-vitamin-could-slash...

    Dementia impacts millions of older adults, but researchers are still learning how, exactly, to prevent this devastating illness. Now, research suggests that increasing your intake of one specific ...

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