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Nerves involved in the resizing of the pupil connect to the pretectal nucleus of the high midbrain, bypassing the lateral geniculate nucleus and the primary visual cortex. From the pretectal nucleus neurons send axons to neurons of the Edinger-Westphal nucleus whose visceromotor axons run along both the left and right oculomotor nerves .
Mydriasis is the dilation of the pupil, usually having a non-physiological cause, [3] or sometimes a physiological pupillary response. [4] Non-physiological causes of mydriasis include disease, trauma, or the use of certain types of drugs. It may also be of unknown cause.
Dilation and constriction of the pupil Pupillary response is a physiological response that varies the size of the pupil between 1.5 mm and 8 mm, [ 1 ] via the optic and oculomotor cranial nerve. A constriction response ( miosis ), [ 2 ] is the narrowing of the pupil, which may be caused by scleral buckles or drugs such as opiates / opioids or ...
Topical atropine is used as a cycloplegic, to temporarily paralyze the accommodation reflex, and as a mydriatic, to dilate the pupils. [15] Atropine degrades slowly, typically wearing off in 7 to 14 days, so it is generally used as a therapeutic mydriatic, whereas tropicamide (a shorter-acting cholinergic antagonist) or phenylephrine (an α-adrenergic agonist) is preferred as an aid to ...
Concerning the 2017 data in the charts below, deaths from the various drugs add up to more than 70,200 because multiple drugs are involved in many of the deaths. [2] According to the National Safety Council, the lifetime odds of dying from an overdose in the United States is 1 in 96. [68] Drug overdose deaths in the US per 100,000 people by state.
Tropicamide, sold under the brand name Mydriacyl among others, is a medication used to dilate the pupil and help with examination of the eye. [3] Specifically it is used to help examine the back of the eye. [4] It is applied as eye drops. [3] Effects occur within 40 minutes and last for up to a day. [3]
Poppers is an inhaled drug which contains a range of alkyl nitrites, such as isobutyl nitrite and amyl nitrite. [11] Despite its primary usage as a potent vasodilator , [ 11 ] its popularity among the homosexual community largely stems from its ability to facilitate anal sexual intercourse by relaxing the smooth muscles in the internal anal ...
Oculogyric crisis (OGC) is a rare sudden, paroxysmal, dystonic reaction that may manifest in response to specific drugs, particularly neuroleptics, or medical conditions, such as movement disorders. This neurological phenomenon is characterized by a sustained dystonic, conjugate , involuntary upward deviation of both eyes lasting seconds to hours.