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A monohybrid cross is a cross between two organisms with different variations at one genetic locus of interest. [ 1 ] [ 2 ] The character(s) being studied in a monohybrid cross are governed by two or multiple variations for a single location of a gene.
In conducting a monohybrid cross, Mendel initiated the experiment with a pair of pea plants exhibiting contrasting traits, one being tall and the other dwarf. Through cross-pollination, the resulting offspring plants manifested the tall trait. These first-generation hybrids were termed F1, with their offspring referred to as Filial or F1 progeny.
"Mono-" means "one"; this cross indicates that the examination of a single trait. This could mean (for example) eye color. Each genetic locus is always represented by two letters. So in the case of eye color, say "B = Brown eyes" and "b = green eyes". In this example, both parents have the genotype Bb. For the example of eye color, this would ...
This definition is still used today. After Plate's definition, Hans Gruneberg was the first to study the mechanisms of pleiotropy. [3] In 1938 Gruneberg published an article dividing pleiotropy into two distinct types: "genuine" and "spurious" pleiotropy. "Genuine" pleiotropy is when two distinct primary products arise from one locus.
Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction.Two genetic markers that are physically near to each other are unlikely to be separated onto different chromatids during chromosomal crossover, and are therefore said to be more linked than markers that are far apart.
In his cross-pollination experiments involving two true-breeding, or homozygous, parents, Mendel found that the resulting F1 generation was heterozygous and consistent. The offspring showed a combination of the phenotypes from each parent that were genetically dominant. Mendel's discoveries involving the F1 and F2 generations laid the ...
Another common term at that time was the theory of evolution, although "evolution" (in the sense of development as a pure growth process) had a completely different meaning than today. The preformists assumed that the entire organism was preformed in the sperm (animalkulism) or in the egg (ovism or ovulism) and only had to unfold and grow.
In genetics, a reciprocal cross is a breeding experiment designed to test the role of parental sex on a given inheritance pattern. [1] All parent organisms must be true breeding to properly carry out such an experiment. In one cross, a male expressing the trait of interest will be crossed with a female not expressing the trait.