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This microRNA database and microRNA targets databases is a compilation of databases and web portals and servers used for microRNAs and their targets. MicroRNAs (miRNAs) represent an important class of small non-coding RNAs (ncRNAs) that regulate gene expression by targeting messenger RNAs. [1]
miRBase: the microRNA database; PolymiRTS: a database of DNA variations in putative microRNA target sites; PolyQ: database of polyglutamine repeats in disease and non-disease associated proteins; Rfam: a database of RNA families; IRESbase: A comprehensive database of experimentally validated internal ribosome entry sites. [14]
miRBase grew from the microRNA registry resource set up by Sam Griffiths-Jones in 2003. [7] According to Ana Kozomara and Sam Griffiths-Jones miRBase has five aims: [1] To provide a consistent naming system for microRNAs; To provide a central place collecting all known microRNA sequences; To provide human and computer readable information for ...
StarBase also developed Pan-Cancer Analysis Platform to decipher Pan-Cancer Analysis Networks of lncRNAs, miRNAs, ceRNAs, and RNA-binding proteins (RBPs) by mining clinical and expression profiles of 14 cancer types (including more than six thousand samples) from The Cancer Genome Atlas (TCGA) Data Portal.
Cupid is a method for simultaneous prediction of miRNA-target interactions and their mediated competing endogenous RNA (ceRNA) interactions. It is an integrative approach significantly improves on miRNA-target prediction accuracy as assessed by both mRNA and protein level measurements in breast cancer cell lines.
Community portal; Recent changes; Upload file; Search. Search. ... In molecular biology mir-23 microRNA is a short RNA molecule. ... [1] See also. MicroRNA;
The microRNA precursor miR-17 family, includes miR-20a/b, miR-93, and miR-106a/b. With the exception of miR-93, these microRNAs are produced from several microRNA gene clusters, which apparently arose from a series of ancient evolutionary genetic duplication events, and also include members of the miR-19, and miR-25 families. [1]
The miR-1 microRNA precursor is a small micro RNA that regulates its target protein's expression in the cell. microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give products at ~22 nucleotides. [1] In this case the mature sequence comes from the 3' arm of the precursor.