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The normal range of GFR, adjusted for body surface area, is 100–130 average 125 (mL/min)/(1.73 m 2) in men and 90–120 (mL/min)/(1.73 m 2) in women younger than the age of 40. In children, GFR measured by inulin clearance is 110 (mL/min)/(1.73 m 2 ) until 2 years of age in both sexes, and then it progressively decreases.
Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. [4] Central to the physiologic maintenance of GFR is the differential basal tone of the afferent (input) and efferent (output) arterioles (see diagram).
A phosphate concentration greater than 1.46 mmol/L (4.5 mg/dL) is indicative of hyperphosphatemia, though further tests may be needed to identify the underlying cause of the elevated phosphate levels. [5] It is considered significant when levels are greater than 1.6 mmol/L (5 mg/dL). [2]
The term phosphate is also used in organic chemistry for the functional groups that result when one or more of the hydrogens are replaced by bonds to other groups. These acids, together with their salts and esters , include some of the best-known compounds of phosphorus, of high importance in biochemistry , mineralogy , agriculture , pharmacy ...
Group 15 consists of the elements nitrogen (N), phosphorus (P), arsenic (As), antimony (Sb), bismuth (Bi), and moscovium (Mc). Since 1988, it has been called Group 15 by the IUPAC . Before that, in America it was called Group V A , owing to a text by H. C. Deming and the Sargent-Welch Scientific Company , while in Europe it was called Group V B ...
Water is split in the reaction, with the -OH group attaching to the phosphate ion, and the H+ protonating the hydroxyl group of the other product. The net result of the reaction is the destruction of a phosphomonoester and the creation of both a phosphate ion and a molecule with a free hydroxyl group. [4]
The absorbance of the blue solution can be measured with a colorimeter and the concentration of phosphate in the original solution can be calculated. Alternatively, a direct (but approximate) reading of phosphate concentration can be obtained by using a Lovibond comparator. This method for phosphate determination is known as Denigés' method ...
Hydrogen phosphate or monohydrogen phosphate (systematic name) is the inorganic ion with the formula [HPO 4] 2-. Its formula can also be written as [PO 3 (OH)] 2-. Together with dihydrogen phosphate, hydrogenphosphate occurs widely in natural systems. Their salts are used in fertilizers and in cooking. [1]