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1. What is osteoporosis? Osteoporosis is a disease of the bones. People with osteoporosis have bones that are weak and break easily. Osteoporosis is called a “silent” disease.
Osteoporosis can affect nearly 1 in 3 women and the bone loss is the most rapid within the first 2–3 years after menopause. This can be prevented by menopause hormone therapy or MHT, which is meant to prevent bone loss and the degradation of the bone microarchitecture and is noted to reduce the risk of fractures in bones by 20-30%.
Osteopenia, known as "low bone mass" or "low bone density", is a condition in which bone mineral density is low. [1] Because their bones are weaker, people with osteopenia may have a higher risk of fractures , and some people may go on to develop osteoporosis . [ 2 ]
Bone loss may refer to a number of entities: Osteopenia, a condition in which overall bone density decreases without causing symptoms; Osteoporosis, a condition in which overall bone density decreases while causing symptoms; Periodontitis, a condition in which the supporting bone around teeth exhibits resorption
Senile osteoporosis has been recently recognized as a geriatric syndrome with a particular pathophysiology. There are different classification of osteoporosis: primary, in which bone loss is a result of aging and secondary, in which bone loss occurs from various clinical and lifestyle factors. [1]
Bone remodeling is a process which maintains bone strength and ion homeostasis by replacing discrete parts of old bone with newly synthesized packets of proteinaceous matrix. [5] Bone is resorbed by osteoclasts, and is deposited by osteoblasts in a process called ossification. [6] Osteocyte activity plays a key role in this process. Conditions ...