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The willingness of the female rats to access males was considered a direct measure of the females' levels of sexual motivation. An increase in vasopressin has been observed in female rats which have just given birth. Vasopressin is associated with aggressive and hostile behaviours, and is postulated to decrease sexual motivation in females.
The Brattleboro rat is a strain of laboratory rat descended from a litter born in West Brattleboro, Vermont in 1961 without the ability to produce the hormone vasopressin, which helps control kidney function. The rats' lack of vasopressin was the result of a naturally occurring genetic mutation. [citation needed]
The well known antidiuretic effect of vasopressin occurs via activation of V 2 R. [1] Vasopressin regulates water excretion from the kidney by increasing the osmotic water permeability of the renal collecting duct – an effect that is explained by coupling of the V 2 R with the G s signaling pathway, which activates cAMP.
Vasopressin receptor 1A (V1AR), or arginine vasopressin receptor 1A (officially called AVPR1A) is one of the three major receptor types for vasopressin (AVPR1B and AVPR2 being the others), and is present throughout the brain, as well as in the periphery in the liver, kidney, and vasculature. [5] AVPR1A is also known as: V1a vasopressin receptor
The oxytocin and vasopressin that is released at the posterior pituitary gland enters the blood, and cannot re-enter the brain because the blood–brain barrier does not allow oxytocin and vasopressin through, but the oxytocin and vasopressin that is released from dendrites acts within the brain. Oxytocin neurons themselves express oxytocin ...
Vasopressin receptor 2 (V2R), or arginine vasopressin receptor 2 (officially called AVPR2), is a protein that acts as receptor for vasopressin. [5] AVPR2 belongs to the subfamily of G-protein-coupled receptors. Its activity is mediated by the G s type of G proteins, which stimulate adenylate cyclase.
26361 Ensembl ENSG00000198049 ENSMUSG00000026432 UniProt P47901 Q9WU02 RefSeq (mRNA) NM_000707 NM_011924 RefSeq (protein) NP_000698 NP_036054 Location (UCSC) Chr 1: 206.11 – 206.12 Mb Chr 1: 131.53 – 131.54 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Vasopressin V1b receptor (V1BR) also known as vasopressin 3 receptor (VPR3) or antidiuretic hormone receptor 1B is a protein ...
This is in contrast to central or neurogenic diabetes insipidus, which is caused by insufficient levels of vasopressin (also called antidiuretic hormone, ADH). Nephrogenic diabetes insipidus is caused by an improper response of the kidney to vasopressin, leading to a decrease in the ability of the kidney to concentrate the urine by removing ...