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Melanin (/ ˈ m ɛ l ə n ɪ n / ⓘ; from Ancient Greek μέλας (mélas) 'black, dark') is a family of biomolecules organized as oligomers or polymers, which among other functions provide the pigments of many organisms. [1] Melanin pigments are produced in a specialized group of cells known as melanocytes.
Hyperpigmentation results from an increase in melanin synthesis, which is mostly brought on by sun exposure, dermatological disorders, hormones, aging, genetic factors, skin injuries or inflammation, and acne. Sun exposure, which greatly increases the synthesis of melanin, is the most common cause of hyperpigmentation. [4]
Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair.
Freckles are clusters of concentrated melaninized cells which are most easily visible on people with a fair complexion.Freckles do not have an increased number of the melanin-producing cells, or melanocytes, but instead have melanocytes that overproduce melanin granules (melanosomes) changing the coloration of the outer skin cells (keratinocytes).
The key is to start slowly and gradually increase the amount of concentration and number of weekly applications once your skin adapts. ... compounds that inhibit melanin production,” says Dr ...
In the second process, triggered primarily by UVB, there is an increase in production of melanin (melanogenesis), [10] which is the body's reaction to direct DNA photodamage (formation of pyrimidine dimers) from UV radiation. [11] Melanogenesis leads to delayed tanning, and typically becomes visible two or three days after exposure. [10]