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An example of a Kaplan–Meier plot for two conditions associated with patient survival. The Kaplan–Meier estimator, [1] [2] also known as the product limit estimator, is a non-parametric statistic used to estimate the survival function from lifetime data. In medical research, it is often used to measure the fraction of patients living for a ...
Kaplan–Meier curves and log-rank tests are most useful when the predictor variable is categorical (e.g., drug vs. placebo), or takes a small number of values (e.g., drug doses 0, 20, 50, and 100 mg/day) that can be treated as categorical.
Survival analysis includes Cox regression (Proportional hazards model) and Kaplan–Meier survival analysis. Procedures for method evaluation and method comparison include ROC curve analysis, [6] Bland–Altman plot, [7] as well as Deming and Passing–Bablok regression. [8]
The Rastelli procedure is an open heart surgical procedure developed by ... avoidance of death or transplantation (Kaplan-Meier) was 82 percent, 80 percent, 68 ...
Paul Meier (July 24, 1924 – August 7, 2011) [1] was a statistician who promoted the use of randomized trials in medicine. [2] [3]Meier is known for introducing, with Edward L. Kaplan, the Kaplan–Meier estimator, [4] [5] a method for measuring how many patients survive a medical treatment from one duration to another, taking into account that the sampled population changes over time.
Kaplan–Meier estimator [ edit ] The Dvoretzky–Kiefer–Wolfowitz inequality is obtained for the Kaplan–Meier estimator which is a right-censored data analog of the empirical distribution function
Kaplan-Meier curve illustrating overall survival based on volume of brain metastases.Elaimy et al. (2011) [6] In its simplest form, the hazard ratio can be interpreted as the chance of an event occurring in the treatment arm divided by the chance of the event occurring in the control arm, or vice versa, of a study.
The problem with measuring overall survival by using the Kaplan-Meier or actuarial survival methods is that the estimates include two causes of death: deaths from the disease of interest and deaths from all other causes, which includes old age, other cancers, trauma and any other possible cause of death. In general, survival analysis is ...