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Sensory neuronopathy (also known as sensory ganglionopathy) is a type of peripheral neuropathy that results primarily in sensory symptoms (such as parasthesias, pain or ataxia) due to destruction of nerve cell bodies in the dorsal root ganglion. [1]
Autoimmune autonomic ganglionopathy is a type of immune-mediated autonomic failure that is associated with antibodies against the ganglionic nicotinic acetylcholine receptor present in sympathetic, parasympathetic, and enteric ganglia. Typical symptoms include gastrointestinal dysmotility, orthostatic hypotension, and tonic pupils. [1]
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
[23] [3] It is classified as a sensory ganglionopathy due to involvement of these ganglia. [61] [b] In electrodiagnostic testing, it has characteristic non-length-dependent abnormalities of sensory action potentials that occur globally, rather than distally decreasing sensory nerve action potential amplitudes. [57]
Sensory neuronopathy (also known as sensory ganglionopathy) is a type of peripheral neuropathy in which sensory nerve cell bodies in the dorsal root ganglia, commonly including the trigeminal ganglion of the trigeminal nerve, are damaged due to a variety of mechanisms leading to sensory symptoms such as parasthesias, dysesthesias, or ...
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The cell bodies of sensory neurons known as first-order neurons are located in the dorsal root ganglia. [2] The axons of dorsal root ganglion neurons are known as afferents. In the peripheral nervous system, afferents refer to the axons that relay sensory information into the central nervous system (i.e. the brain and the spinal cord).
It contains cell bodies of first-order unipolar sensory neurons which convey gustatory (taste) afferents from taste receptors of the anterior two-thirds of the tongue by way of the chorda tympani, and of the palate by way of the greater petrosal nerve, From the ganglion, the proximal fibres proceed to the gustatory (i.e. superior/rostral [3 ...