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Common side effects for oral decongestants include insomnia, hypertension (elevated blood pressure), and difficulty in urination. [12] Avoid use during pregnancy as it may cause vasoconstriction of uterine arteries thus reducing fetal blood supply. [14] Zyrtec-D, an example of combination therapy. Combination therapy with antihistamines
Decongestants can be absorbed from the nose via an inhaler and produce systemic effects, mainly central nervous system stimulation and rise in blood pressure. These drugs should be used cautiously in hypertensives and in those receiving monoamine oxidase inhibitors (MAOIs), as they can cause hypertensive crisis .
For most people, recommendations are to reduce blood pressure to less than or equal to somewhere between 140/90 mmHg and 160/100 mmHg. [2] In general, for people with elevated blood pressure, attempting to achieve lower levels of blood pressure than the recommended 140/90 mmHg will create more harm than benefits, [3] in particular for older people. [4]
“A common myth is that you will not develop high blood pressure if you do not have a family history of high blood pressure or heart disease,” says Marjorie Nolan Cohn, M.S., RD, LDN, a ...
Over time, high blood pressure can cause damage to the arteries that can lead to health conditions including stroke, heart disease, kidney problems and dementia. There are multiple risk factors ...
Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies. [1] Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides relief from nasal congestion, sneezing, or hives caused by pollen, dust mites, or animal allergy with few side effects. [1]
To put this into perspective, some research shows that reducing your systolic blood pressure (top blood pressure reading) by 5 mmHg may lower your risk of cardiovascular events by 10%! The Bottom Line
Diphenhydramine is a potent antimuscarinic (a competitive antagonist of muscarinic acetylcholine receptors) and, as such, at high doses can cause anticholinergic syndrome. [68] The utility of diphenhydramine as an antiparkinson agent is the result of its blocking properties on the muscarinic acetylcholine receptors in the brain.