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  2. Fatty acid synthesis - Wikipedia

    en.wikipedia.org/wiki/Fatty_acid_synthesis

    In biochemistry, fatty acid synthesis is the creation of fatty acids from acetyl-CoA and NADPH through the action of enzymes called fatty acid synthases. This process takes place in the cytoplasm of the cell. Most of the acetyl-CoA which is converted into fatty acids is derived from carbohydrates via the glycolytic pathway.

  3. Lipogenesis - Wikipedia

    en.wikipedia.org/wiki/Lipogenesis

    Lipogenesis encompasses both fatty acid and triglyceride synthesis, with the latter being the process by which fatty acids are esterified to glycerol before being packaged into very-low-density lipoprotein (VLDL). Fatty acids are produced in the cytoplasm of cells by repeatedly adding two

  4. Fatty-acyl-CoA synthase - Wikipedia

    en.wikipedia.org/wiki/Fatty-acyl-CoA_synthase

    The malfunction of the fatty acid synthesis pathway can result in cancer and obesity. However, the significance of fatty acid synthesis also make the fatty acid synthesis pathway a potential target for the search and study of anticancer and antibiotic drugs. [2] It has been found that in humans, fatty acid synthase, is overly expressed in ...

  5. Fatty acid synthase - Wikipedia

    en.wikipedia.org/wiki/Fatty_acid_synthase

    n/a n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a n/a Wikidata View/Edit Human Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene. Fatty acid synthase is a multi-enzyme protein that catalyzes fatty acid synthesis. It is not a single enzyme but a whole enzymatic system composed of two ...

  6. Fatty acid - Wikipedia

    en.wikipedia.org/wiki/Fatty_acid

    Saturated fatty acids 16 and 18 carbons in length are the dominant types in the epidermis, [38] [39] while unsaturated fatty acids and saturated fatty acids of various other lengths are also present. [ 38 ] [ 39 ] The relative abundance of the different fatty acids in the epidermis is dependent on the body site the skin is covering. [ 39 ]

  7. Fatty acid metabolism - Wikipedia

    en.wikipedia.org/wiki/Fatty_acid_metabolism

    Most fatty acids in human plasma are 16 or 18 carbon atoms long. CAT is inhibited by high concentrations of malonyl-CoA (the first committed step in fatty acid synthesis) in the cytoplasm. This means that fatty acid synthesis and fatty acid catabolism cannot occur simultaneously in any given cell.

  8. Phosphatidylethanolamine - Wikipedia

    en.wikipedia.org/wiki/Phosphatidylethanolamine

    As a lecithin, phosphatidylethanolamine consists of a combination of glycerol esterified with two fatty acids and phosphoric acid. Whereas the phosphate group is combined with choline in phosphatidylcholine, it is combined with ethanolamine in phosphatidylethanolamine. The two fatty acids may be identical or different, and are usually found in ...

  9. Acetyl-CoA - Wikipedia

    en.wikipedia.org/wiki/Acetyl-CoA

    It is produced during the breakdown of glucose, fatty acids, and amino acids, and is used in the synthesis of many other biomolecules, including cholesterol, fatty acids, and ketone bodies. Acetyl-CoA is also a key molecule in the citric acid cycle , which is a series of chemical reactions that occur in the mitochondria of cells and is ...