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  2. Rabbit hybridoma - Wikipedia

    en.wikipedia.org/wiki/Rabbit_hybridoma

    The rabbit formed a myeloma-like tumor, allowing the isolation of a plasmacytoma cell line, named 240E-1. Fusion of 240E-1 cells with rabbit lymphocytes produced hybridomas that secreted rabbit monoclonal antibodies in a consistent manner. [4] However, like the early mouse myeloma lines developed in the 1970s, stability was a concern.

  3. Hybridoma technology - Wikipedia

    en.wikipedia.org/wiki/Hybridoma_technology

    One study has reported the isolation of a hybridoma cell line (clone 1E10), which produces a monoclonal antibody (IgM, k isotype). This monoclonal antibody shows specific immuno-cytochemical staining of nucleoli. [12] Tissues and tumours can be classified based on their expression of certain markers, with the help of monoclonal antibodies.

  4. Anti-thymocyte globulin - Wikipedia

    en.wikipedia.org/wiki/Anti-thymocyte_globulin

    Anti-thymocyte globulin (ATG) is an infusion of horse or rabbit-derived antibodies against human T cells and their precursors , which is used in the prevention and treatment of acute rejection in organ transplantation and therapy of aplastic anemia due to bone marrow insufficiency.

  5. Anti-gliadin antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-gliadin_antibodies

    Anti-gliadin antibodies can be generated in mice or rabbits by immunizing whole purified gliadins, proteolytic fragments of gliadin, or synthetic peptides that represent epitopes of gliadin. After developing an immune response, B-cells from mice can be fused with immortalizing cells to form a hybridoma that produces monoclonal antibodies (Mab ...

  6. Monoclonal antibody - Wikipedia

    en.wikipedia.org/wiki/Monoclonal_antibody

    A general representation of the method used to produce monoclonal antibodies [1] [2] A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell.

  7. Thymoglobulin - Wikipedia

    en.wikipedia.org/wiki/Thymoglobulin

    Thymoglobulin (manufactured by Sanofi) is an anti-human thymocyte immunoglobulin preparation made of purified polyclonal antibodies derived from rabbits. While these antibodies have a variety of specificities, their main mechanism of immunosuppression is through depletion of T cells.

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