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Three-dimensional schematic of the interstitium, a fluid-filled space supported by a network of collagen. In anatomy, the interstitium is a contiguous fluid-filled space existing between a structural barrier, such as a cell membrane or the skin, and internal structures, such as organs, including muscles and the circulatory system.
Claude Bernard, French physician who introduced the concept of homeostasis. The human body and even its individual body fluids may be conceptually divided into various fluid compartments, which, although not literally anatomic compartments, do represent a real division in terms of how portions of the body's water, solutes, and suspended elements are segregated.
Extracellular fluid may be mechanically guided in this circulation by the vesicles between other structures. Collectively this forms the interstitium, which may be considered a newly identified biological structure in the body. [36] However, there is some debate over whether the interstitium is an organ. [37]
Scientists said in a study published Tuesday that they may have stumbled on an unknown organ that could significantly advance our understanding of cancer.
The interstitium of the kidney increases in osmolarity outside as the loop of Henle descends from 600 mOsm/L in the outer medulla of the kidney to 1200 mOsm/L in the inner medulla. The descending portion of the loop of Henle is extremely permeable to water and is less permeable to ions, therefore water is easily reabsorbed here and solutes are ...
Interstitium, the contiguous fluid-filled space existing between the skin and body organs; Other uses. To describe the spaces within particulate matter such as sands ...
The medullary interstitium is the tissue surrounding the loop of Henle in the medulla. It functions in renal water reabsorption by building up a high hypertonicity , which draws water out of the thin descending limb of the loop of Henle and the collecting duct system .
Interstitial nephritis may present with a variety of signs and symptoms, many of these nonspecific. Fever is the most common, occurring in 30-50% of patients, particularly those with drug-induced interstitial nephritis. [2]