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Sensitivity analysis is the study of how the uncertainty in the output of a mathematical model or system (numerical or otherwise) can be divided and allocated to different sources of uncertainty in its inputs. [1] [2] This involves estimating sensitivity indices that quantify the influence of an input or group of inputs on the output.
[1] [2] In biomedical engineering, sensitivity analysis can be used to determine system dynamics in ODE-based kinetic models. Parameters corresponding to stages of differentiation can be varied to determine which parameter is most influential on cell fate.
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FAST is more efficient to calculate sensitivities than other variance-based global sensitivity analysis methods via Monte Carlo integration. However the calculation by FAST is usually limited to sensitivities referred to as “main effects” or “first-order effects” due to the computational complexity in computing higher-order effects.
OpenStudio Analysis Framework and Spreadsheet: [9] A front-end for the OpenStudio Server, allowing for users to create large-scale cloud analyses using OpenStudio measures. SALib: [10] A Python library for general sensitivity analysis, which can be used with user-defined scripts to run EnergyPlus and extract results.
Variance-based sensitivity analysis (often referred to as the Sobol’ method or Sobol’ indices, after Ilya M. Sobol’) is a form of global sensitivity analysis. [1] [2] Working within a probabilistic framework, it decomposes the variance of the output of the model or system into fractions which can be attributed to inputs or sets of inputs.
A sensitivity analysis may reveal surprising insights in multi-criteria decision making (MCDM) studies aimed to select the best alternative among a number of competing alternatives. This is an important task in decision making. In such a setting each alternative is described in terms of a set of evaluative criteria.
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