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2. Breast cancer classification - Wikipedia

   en.wikipedia.org/wiki/Breast_cancer_classification

   Well differentiated is given a grade of 1, moderate is grade 2, while poor or undifferentiated is given a higher grade of 3 or 4 (depending upon the scale used). The Nottingham system [ 12 ] is recommended for breast cancer grading. [ 13 ]

3. Breast cancer - Wikipedia

   en.wikipedia.org/wiki/Breast_cancer

   Each feature is scored on a three-point scale, with a higher score indicating less healthy looking tissue. A grade is assigned based on the sum of the three scores. Combined scores of 3, 4, or 5 represent grade 1, a slower-growing cancer. Scores of 6 or 7 represent grade 2. Scores of 8 or 9 represent grade 3, a faster-growing, more aggressive ...

4. TNM staging system - Wikipedia

   en.wikipedia.org/wiki/TNM_staging_system

   G (1–4): the grade of the cancer cells (i.e. they are "low grade" if they appear similar to normal cells, and "high grade" if they appear poorly differentiated) S (0–3): elevation of serum tumor markers; R (0–2): the completeness of the operation (resection-boundaries free of cancer cells or not) Pn (0–1): invasion into adjunct nerves

5. Grading (tumors) - Wikipedia

   en.wikipedia.org/wiki/Grading_(tumors)

   Grading in cancer is distinguished from staging, which is a measure of the extent to which the cancer has spread. Pathology grading systems classify the microscopic cell appearance abnormality and deviations in their rate of growth with the goal of predicting developments at tissue level (see also the 4 major histological changes in dysplasia ).

6. Breast cancer management - Wikipedia

   en.wikipedia.org/wiki/Breast_cancer_management

   Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.

7. Cancer staging - Wikipedia

   en.wikipedia.org/wiki/Cancer_staging

   3D medical illustration depicting the TNM stages in breast cancer. Cancer staging can be divided into a clinical stage and a pathologic stage. In the TNM (Tumor, Node, Metastasis) system, clinical stage and pathologic stage are denoted by a small "c" or "p" before the stage (e.g., cT3N1M0 or pT2N0).