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Syrup of ipecac (/ ˈ ɪ p ɪ k æ k /), or simply ipecac, is a drug that was once widely used as an expectorant (in low doses) and a rapid-acting emetic (in higher doses). It is obtained from the dried rhizome and roots of the ipecacuanha plant ( Carapichea ipecacuanha ), from which it derives its name.
Inducing vomiting with syrup of ipecac has no role in paracetamol overdose because the vomiting it induces delays the effective administration of activated charcoal and oral acetylcysteine. [19] Liver injury is extremely rare after acute accidental ingestion in children under 6 years of age.
Cephaeline induces vomiting by stimulating the stomach lining and is found in commercial products such as syrup of ipecac. [2] Chemically, it is closely related to emetine . Poison treatment
Although this therapy was reportedly successful, the extract caused vomiting in many patients, which reduced its utility. In some cases, it was given with opioids to reduce nausea . Other approaches to reduce nausea involved coated tablets, allowing the drug to be released after digestion in the stomach.
The most common and familiar preparation is syrup of ipecac, which was commonly recommended as an emergency treatment for accidental poisoning until the final years of the 20th century. [5] Ipecacuanha was also traditionally used to induce sweating. A common preparation for this purpose was Dover's powder.
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Emesis (i.e. induced by ipecac) is no longer recommended in poisoning situations, because vomiting is ineffective at removing poisons. [16] Gastric lavage, commonly known as a stomach pump, is the insertion of a tube into the stomach, followed by administration of water or saline down the tube. The liquid is then removed along with the contents ...
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