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The number of people with depression has reached new highs—and so has antidepressant use. As Americans are increasingly reaching for pharmaceutical solutions for depression—about one in eight ...
Switching to a new type of antidepressant may help reverse any weight gain you’ve experienced during treatment. Research shows that approximately one-third of people with depression have ...
The term is fairly new, ... For mild to moderate symptoms, therapy is considered first-line treatment for postpartum depression and anxiety, says Dr. Meltzer-Brody. Well-trained providers ...
Ketamine has been tested as a rapid-acting antidepressant [22] for treatment-resistant depression in bipolar disorder, and major depressive disorder. [23] Spravato, a nasal spray form of esketamine, was approved by the FDA in 2019 for use in treatment-resistant depression when combined with an oral antidepressant. [24] [25]
Stephen M. Stahl, renowned academician in psychopharmacology, has stated resorting to a dynamic psychostimulant, in particular, d-amphetamine is the "classical augmentation strategy for treatment-refractory depression". [84] However, the use of stimulants in cases of treatment-resistant depression is relatively controversial. [85] [86]
Aticaprant, also known by its developmental codes JNJ-67953964, CERC-501, and LY-2456302, is a κ-opioid receptor (KOR) antagonist which is under development for the treatment of major depressive disorder. [2] [3] [4] A regulatory application for approval of the medication is expected to be submitted by 2025. [2] Aticaprant is taken by mouth. [1]
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