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Isosorbide dinitrate is in the nitrate family of medications and works by dilating blood vessels. [1] Isosorbide dinitrate was first written about in 1939. [3] It is on the World Health Organization's List of Essential Medicines. [4] Isosorbide dinitrate is available as a generic medication. [1] [5] A long-acting form exists. [1]
Hummers' method is a chemical process that can be used to generate graphite oxide through the addition of potassium permanganate to a solution of graphite, sodium nitrate, and sulfuric acid. It is commonly used by engineering and lab technicians as a reliable method of producing quantities of graphite oxide.
A common nitrate test, known as the brown ring test [2] can be performed by adding iron(II) sulfate to a solution of a nitrate, then slowly adding concentrated sulfuric acid such that the acid forms a layer below the aqueous solution. A brown ring will form at the junction of the two layers, indicating the presence of the nitrate ion. [3]
The first long-acting (depot) injections were antipsychotics fluphenazine and haloperidol. [2] The concept of a depot injection arose before 1950, and originally was used to describe antibiotic injections that lasted longer to allow for less frequent administration.
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The medical application was never widespread, the standard nitroglycerine being faster acting and very inexpensive; oral nitrates in any case being only palliative, not an effective treatment. Triethylene glycol dinitrate , diethylene glycol dinitrate, and trimethylolethane trinitrate are being considered as replacements for nitroglycerin in ...
That said, if you use nitrates for angina (chest pain) or alpha-blockers and certain other medications to treat hypertension (high blood pressure), the reduction in blood pressure caused by ED ...
Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage).