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  2. Connective tissue disease - Wikipedia

    en.wikipedia.org/wiki/Connective_tissue_disease

    Connective tissue disease, also known as connective tissue disorder, or collagen vascular diseases, refers to any disorder that affects the connective tissue. [1] The body's structures are held together by connective tissues, consisting of two distinct proteins : elastin and collagen .

  3. Marfan syndrome - Wikipedia

    en.wikipedia.org/wiki/Marfan_syndrome

    Marfan syndrome (MFS) is a multi-systemic genetic disorder that affects the connective tissue. [6] [7] [1] Those with the condition tend to be tall and thin, with long arms, legs, fingers, and toes. [1] They also typically have exceptionally flexible joints and abnormally curved spines. [1]

  4. Rheumatic fever - Wikipedia

    en.wikipedia.org/wiki/Rheumatic_fever

    The majority of morbidity and mortality associated with rheumatic fever is caused by its destructive effects on cardiac valve tissue. [18] The complicated pathogenesis of RHD is not fully understood, though it has been observed to use molecular mimicry via group A streptococci carbohydrates and genetic predisposition involving HLA Class II ...

  5. Collagen disease - Wikipedia

    en.wikipedia.org/wiki/Collagen_disease

    Collagen disease is a term previously used to describe systemic autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus, and systemic sclerosis), but now is thought to be more appropriate for diseases associated with defects in collagen, which is a component of the connective tissue. [1] The term "collagen disease" was ...

  6. Hypermobility (joints) - Wikipedia

    en.wikipedia.org/wiki/Hypermobility_(joints)

    Hypermobility can also be caused by connective tissue disorders, such as Ehlers–Danlos syndrome (EDS) and Marfan syndrome. Joint hypermobility is a common symptom for both. EDS has numerous sub-types; most include hypermobility in some degree. When hypermobility is the main symptom, then EDS/hypermobility type is likely.

  7. CREST syndrome - Wikipedia

    en.wikipedia.org/wiki/CREST_syndrome

    CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder.The acronym "CREST" refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.

  8. Fibrodysplasia ossificans progressiva - Wikipedia

    en.wikipedia.org/wiki/Fibrodysplasia_ossificans...

    Fibrodysplasia ossificans progressiva (/ ˌ f aɪ b r oʊ d ɪ ˈ s p l eɪ ʒ (i) ə ɒ ˈ s ɪ f ɪ k æ n z p r ə ˈ ɡ r ɛ s ɪ v ə /; [1] abbr. FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification).

  9. Undifferentiated connective tissue disease - Wikipedia

    en.wikipedia.org/wiki/Undifferentiated...

    Undifferentiated connective tissue disease (UCTD) (also known as latent lupus or incomplete lupus [1]) is a disease in which the connective tissues are targeted by the immune system. It is a serological and clinical manifestation of an autoimmune disease .