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Debate continues over the ethics and regulations of research involving human subjects because of discrepancies over the meaning and priority of the Belmont Report ' s basic ethical principles: respect for persons, beneficence, and justice. Notably, the Belmont Report does not specify how its three ethical principles should be weighted or ...
Beneficence is a concept in research ethics that states that researchers should have the welfare of the research participant as a goal of any clinical trial or other research study. The antonym of this term, maleficence , describes a practice that opposes the welfare of any research participant.
The three basic ethical principles outlined in the Belmont Report are respect for persons, beneficence, and justice. [17] Respect for persons incorporates emphasis on the subjects and their autonomy, meaning their ability to make decisions in the research. To have autonomy, subjects must give informed consent.
In research ethics, justice regards fairness in the distribution of burdens and benefits of research. For example, justice is a consideration in recruiting volunteer research participants, in considering any existing burdens the groups from which they are recruited face (such as historic marginalisation) and the risks of the research, alongside the potential benefits of the research.
The three guidelines are beneficence, justice and respect for persons. Beneficence is described as protecting the well-being of the persons and respecting their decisions by being ethical and protecting the subjects from harm. The two rules of beneficence are maximizing the benefits of research and minimizing any possible risks. [14]
The Belmont Report: Ethical Principles and Guidelines for Protection of Human Subjects of Biomedical and Behavioral Research (1979) These reports contained their recommendations, [ 10 ] the underlying deliberations and conclusions, [ 11 ] a dissenting statement and additional statement by commission members and summaries of materials presented ...
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The result of these abuses was the National Research Act of 1974 and the development of the Belmont Report, which outlined the primary ethical principles in human subjects review; these include "respect for persons", "beneficence", and "justice". An IRB may approve only research for which the risks to subjects are balanced by potential benefits ...