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In the presence of neurological symptoms, following daily treatment, injections up to weekly or biweekly are indicated for six months before initiating monthly IM injections. Once clinical improvement is confirmed, maintenance supplementation of B 12 will generally be needed for life.
More serious vitamin B 12 deficiency requires injections initially. [3] A 2019 study suggested that oral B 12 is inferior to B 12 injections in severe cases, as "there is no proof in large prospective, double-blind studies that oral supplementation is as effective in reducing symptoms associated with vitamin B 12 deficiency as parenteral ...
Cyanocobalamin is a form of vitamin B 12 used to treat and prevent vitamin B 12 deficiency except in the presence of cyanide toxicity. [7] [8] [2] The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer. [9] [5] It is used by mouth, by injection into a muscle, or as a ...
Pernicious anemia can be treated with injections of vitamin B 12. [7] If the symptoms are serious, frequent injections are typically recommended initially. [7] There are not enough studies that pills are effective in improving or eliminating symptoms. [12] Often, treatment may be needed for life. [13]
[39]: 973 Breast milk B 12 decreases over months of nursing in both well-nourished and vitamin-deficient mothers. [39]: 973–974 Exclusive or near-exclusive breastfeeding beyond six months is a strong indicator of low serum vitamin status in nursing infants. This is especially true when the vitamin status is poor during the pregnancy and if ...
Methylcobalamin (mecobalamin, MeCbl, or MeB 12) is a cobalamin, a form of vitamin B 12. It differs from cyanocobalamin in that the cyano group at the cobalt is replaced with a methyl group . [ 1 ] Methylcobalamin features an octahedral cobalt(III) centre and can be obtained as bright red crystals. [ 2 ]